Area of brain linked to bipolar disorder

Bipolar disorder is a major issue; nearly 6 million of American people are suffering from this disorder. It shows changes in mood, energy levels and depressive state also affects sleep and ability to think clearly, according to the study. It also interferes with a person’s ability to work and to perform his daily activities, and could lead to suicide attempts.

To discover the differences in the volumes of subfields of the hippocampus, a seahorse-shaped region in the brain. Research team has used a combination of MRI and start-of-the-art segmentation. In this subjects with bipolar disorder and subjects with healthy and subjects with depressive disorder are compared

The study of compared subjects shows that bipolar disorder has a reduced volumes in  the subfield 4 of the cornu Ammonis (CA).This was more severe with patients of Bipolar disorder 1 than other mood disorders.

As the illness duration increases in Bipolar 1 disorder the volumes of certain areas as right CA 1 is decreased and those CA areas and hippocampal tail was more reduced who are subjected with more manic episodes.